Nicos autoclave steam sterilizers meet or exceed the latest cGMP requirements. In addition to our standard models, Nicos is capable of designing and manufacturing customized autoclave sterilizers to meet specific project requirements, including chamber size, performance parameters, level of automation, and other process needs.
Nicos’ steam sterilization capabilities are highly flexible and engineered to support advanced pharmaceutical applications. While superheated water and air/steam mixture autoclave sterilizers are highly specialized units, Nicos can manufacture systems that combine either of these specialized cycles with the conventional steam sterilization cycle.
Furthermore, Nicos can integrate all three sterilization cycles: steam, superheated water, and air/steam mixture, into a single unit, providing a versatile solution for complex production and laboratory requirements.
Our steam sterilizer autoclaves are designed with a chamber and door(s) polished to a precise roughness average (RA), ensuring optimal conditions for the autoclave sterilization process. They guarantee excellent steam distribution, and all customers consistently achieve temperature deviations not exceeding 0.2 °C during validation, an essential requirement for reliable autoclaving sterilization. Each sterilization autoclave is equipped with a full jacket that is dimple‑welded to the chamber, offering superior performance compared to the continuous channels used by other manufacturers and supporting stable autoclave sterilization temperature and time and pressure.
The door frames of our autoclave sterilizers are manufactured from solid 316L stainless steel and feature a dovetail‑shaped groove that houses the sealing gasket. The door seals through gasket pressurization with sterile air or pure steam, and the gasket retracts into the groove when pressure is released, eliminating the need for vacuum pulling and ensuring long‑term reliability in every autoclave steam sterilizer.
To meet a wide range of operational requirements, Nicos offers five different door systems for its steam sterilizer autoclaves, with the sliding door being the most widely used and cost‑effective option thanks to its unique sealing system and extended gasket life. Door opening and closing rely on a heavy‑duty mechanical system consisting of a knuckled threaded screw and nut, ensuring durability and consistent performance.
All pipework of the sterilization autoclave, except for the instrument air line, is built in 316L stainless steel, while the entire framework of the steam sterilization autoclave is constructed from tubular 304 stainless steel. Each unit is enclosed with removable 304 stainless steel panels featuring built‑in access doors and a 180‑grit satin finish (RA 36–45 micro‑inches), combining structural integrity with ease of maintenance.
Our sterilizer autoclave solutions are customized for the global marketplace using readily available and preferred components supported by a worldwide distributor network. All components of the autoclave sterilizers that come into direct or potential contact with the sterile side during operation or maintenance are made exclusively of stainless steel, never carbon steel, cast iron, bronze, or brass, materials still found in competing autoclave machines.
Every standard Nicos steam sterilizer autoclave can be supplied with a 21 CFR Part 11–compliant control system, and all standard Nicos steam sterilization autoclaves are equipped with Siemens or Allen‑Bradley PLCs, an industrial‑grade PC, and a real‑time printer, with the iFIX platform available.
Services provided out of the Norwood New Jersey facility
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